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ULB CENTER FOR DIABETES RESEARCH

90 entries « 1 of 2 »

2024

Kunie Ando; Fahri Küçükali; Emilie Doeraene; Siranjeevi Nagaraj; Eugenia Maria Antonelli; May Thazin Htut; Zehra Yilmaz; Andreea-Claudia Kosa; Lidia Lopez-Guitierrez; Carolina Quintanilla-Sánchez; Emmanuel Aydin; Ana Raquel Ramos; Salwa Mansour; Sabrina Turbant; Stéphane Schurmans; Kristel Sleegers; Christophe Erneux; Jean-Pierre Brion; Karelle Leroy;

Alteration of gene expression and protein solubility of the PI 5-phosphatase SHIP2 are correlated with Alzheimer’s disease pathology progression Journal Article

In: Acta Neuropathol, vol. 147, no. 1, pp. 94, 2024, ISSN: 1432-0533.

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Chun-Liang Yang; Fa-Xi Wang; Jia-Hui Luo; Shan-Jie Rong; Wan-Ying Lu; Qi-Jie Chen; Jun Xiao; Ting Wang; Dan-Ni Song; Jing Liu; Qian Mo; Shuo Li; Yu Chen; Ya-Nan Wang; Yan-Jun Liu; Tong Yan; Wei-Kuan Gu; Shu Zhang; Fei Xiong; Qi-Lin Yu; Zi-Yun Zhang; Ping Yang; Shi-Wei Liu; Decio Eizirik; Ling-Li Dong; Fei Sun; Cong-Yi Wang

PDIA3 orchestrates effector T cell program by serving as a chaperone to facilitate the non-canonical nuclear import of STAT1 and PKM2 Journal Article

In: Mol Ther, 2024, ISSN: 1525-0024.

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Anoop Arunagiri; Maroof Alam; Leena Haataja; Hassan Draz; Bashiyer Alasad; Praveen Samy; Nadeed Sadique; Yue Tong; Ying Cai; Hadis Shakeri; Federica Fantuzzi; Hazem Ibrahim; Insook Jang; Vaibhav Sidarala; Scott A. Soleimanpour; Leslie S. Satin; Timo Otonkoski; Miriam Cnop; Pamela Itkin‐Ansari; Randal J. Kaufman; Ming Liu; Peter Arvan

Proinsulin folding and trafficking defects trigger a common pathological disturbance of endoplasmic reticulum homeostasis Journal Article

In: Protein Science, vol. 33, no. 4, 2024, ISSN: 1469-896X.

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Alexandra Coomans de Brachène; Maria Ines Alvelos; Florian Szymczak; Priscila L Zimath; Angela Castela; Bianca Marmontel de Souza; Arturo Roca Rivada; Sandra Marín-Cañas; Xiaoyan Yi; Anne Op de Beeck; Noel G Morgan; Sebastian Sonntag; Sayro Jawurek; Alexandra C Title; Burcak Yesildag; François Pattou; Julie Kerr-Conte; Eduard Montanya; Montserrat Nacher; Lorella Marselli; Piero Marchetti; Sarah J Richardson; Decio L Eizirik

Interferons are key cytokines acting on pancreatic islets in type 1 diabetes Journal Article

In: Diabetologia, 2024, ISSN: 1432-0428.

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Dario F De Jesus; Zijie Zhang; Natalie K Brown; Xiaolu Li; Ling Xiao; Jiang Hu; Matthew J Gaffrey; Garrett Fogarty; Sevim Kahraman; Jiangbo Wei; Giorgio Basile; Tariq M Rana; Clayton Mathews; Alvin C Powers; Audrey V Parent; Mark A Atkinson; Sirano Dhe-Paganon; Decio L Eizirik; Wei-Jun Qian; Chuan He; Rohit N Kulkarni

Redox regulation of mA methyltransferase METTL3 in β-cells controls the innate immune response in type 1 diabetes Journal Article

In: Nat Cell Biol, 2024, ISSN: 1476-4679.

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Anthony Piron; Florian Szymczak; Theodora Papadopoulou; Maria Inês Alvelos; Matthieu Defrance; Tom Lenaerts; Décio L Eizirik; Miriam Cnop

RedRibbon: A new rank–rank hypergeometric overlap for gene and transcript expression signatures Journal Article

In: Life Science Alliance, vol. 7, no. 2, 2024.

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2023

Hugo Lee; Gulcan Semra Sahin; Chien-Wen Chen; Shreyash Sonthalia; Sandra Marín Cañas; Hulya Zeynep Oktay; Alexander T Duckworth; Gabriel Brawerman; Peter J Thompson; Maria Hatzoglou; Decio L Eizirik; Feyza Engin

Stress-induced β cell early senescence confers protection against type 1 diabetes Journal Article

In: Cell Metab, vol. 35, no. 12, pp. 2200–2215.e9, 2023, ISSN: 1932-7420.

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Emilie Moens de Hase; Audrey M Neyrinck; Julie Rodriguez; Miriam Cnop; Nicolas Paquot; Jean-Paul Thissen; Yining Xu; Ana Beloqui; Laure B Bindels; Nathalie M Delzenne; Matthias Van Hul; Patrice D Cani

Impact of metformin and Dysosmobacter welbionis on diet-induced obesity and diabetes: from clinical observation to preclinical intervention Journal Article

In: Diabetologia, 2023, ISSN: 1432-0428.

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Alexia Carré; Zhicheng Zhou; Javier Perez-Hernandez; Fatoumata Samassa; Christiana Lekka; Anthony Manganaro; Masaya Oshima; Hanqing Liao; Robert Parker; Annalisa Nicastri; Barbara Brandao; Maikel L. Colli; Decio L. Eizirik; Marcus Göransson; Orlando Burgos Morales; Amanda Anderson; Laurie Landry; Farah Kobaisi; Raphael Scharfmann; Lorella Marselli; Piero Marchetti; Sylvaine You; Maki Nakayama; Sine R. Hadrup; Sally C. Kent; Sarah J. Richardson; Nicola Ternette; Roberto Mallone

Interferon-α promotes neo-antigen formation and preferential HLA-B-restricted antigen presentation in pancreatic β-cells Working paper

bioRxiv, 2023.

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J Cantley; D L Eizirik; E Latres; C M Dayan

Islet cells in human type 1 diabetes: from recent advances to novel therapies – a symposium-based roadmap for future research Journal Article

In: J Endocrinol, vol. 259, no. 1, 2023, ISSN: 1479-6805.

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Jing Zhang; Yuan Zou; Longmin Chen; Fei Sun; Qianqian Xu; Qing Zhou; Yi Wang; Xi Luo; Na Wang; Yang Li; Shu Zhang; Fei Xiong; Ping Yang; Shiwei Liu; Tao Yang; Jianping Weng; Décio L Eizirik; Jinhua Yan; Zhiguang Zhou; Cong-Yi Wang

Myo9b mutations are associated with altered dendritic cell functions and increased susceptibility to autoimmune diabetes onset Journal Article

In: Nat Commun, vol. 14, no. 1, pp. 5977, 2023, ISSN: 2041-1723.

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Alexandra Coomans de Brachène; Maria Ines Alvelos; Florian Szymczak; Priscila Laiz Zimath; Angela Castela; Bianca Marmontel de Souza; Arturo Roca Rivada; Sandra Marín-Caňas; Xiaoyan Yi; Anne Op de Beeck; Noel G Morgan; Sebastian Sonntag; Sayro Jawurek; Alexandra C Title; Burcak Yesildag; Francois Pattou; Julie Kerr-Conte; Eduard Montanya; Montserrat Nacher; Lorella Marselli; Piero Marchetti; Sarah J Richardson; Decio L Eizirik

Interferons are the key cytokines acting on pancreatic islets in type 1 diabetes Working paper

bioRxiv, 2023.

Abstract | Links

Bruno Blanchi; Marion Taurand; Claire Colace; Sofia Thomaidou; Charlotte Audeoud; Federica Fantuzzi; Toshiaki Sawatani; Sevda Gheibi; Joan Sabadell-Basallote; Fransje W J Boot; Thibault Chantier; Aline Piet; Charlotte Cavanihac; Marion Pilette; Adélie Balguerie; Hamza Olleik; Françoise Carlotti; Miriam Ejarque; Malin Fex; Hindrik Mulder; Miriam Cnop; Decio L Eizirik; Ouardane Jouannot; Anne-Lise Gaffuri; Paul Czernichow; Arnaud Zaldumbide; Raphaël Scharfmann; Philippe Ravassard

EndoC-βH5 cells are storable and ready-to-use human pancreatic beta cells with physiological insulin secretion Journal Article

In: Mol Metab, pp. 101772, 2023, ISSN: 2212-8778.

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Maria Lytrivi; Carolina Gomes Da Silveira Cauduro; Jésabelle Kibanda; Paulus Kristanto; Marianne Paesmans; Miriam Cnop

Impact of saturated compared with unsaturated dietary fat on insulin sensitivity, pancreatic β-cell function and glucose tolerance: a systematic review and meta-analysis of randomized, controlled trials Journal Article

In: Am J Clin Nutr, 2023, ISSN: 1938-3207.

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Moisés Castellá; Albert Blasco-Roset; Marion Peyrou; Aleix Gavaldà-Navarro; Joan Villarroya; Tania Quesada-López; Leyre Lorente-Poch; Juan Sancho; Florian Szymczak; Anthony Piron; Sonia Rodríguez-Fernández; Stefania Carobbio; Albert Goday; Pere Domingo; Antonio Vidal-Puig; Marta Giralt; Décio L Eizirik; Francesc Villarroya; Rubén Cereijo

Adipose tissue plasticity in pheochromocytoma patients suggests a role of the splicing machinery in human adipose browning Journal Article

In: iScience, vol. 26, no. 6, pp. 106847, 2023, ISSN: 2589-0042.

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Decio L Eizirik; Florian Szymczak; Roberto Mallone

Why does the immune system destroy pancreatic β-cells but not α-cells in type 1 diabetes? Journal Article

In: Nat Rev Endocrinol, 2023, ISSN: 1759-5037.

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Alexandra Coomans de Brachène; Corentin Scoubeau; Anyïshai E Musuaya; Jose Maria Costa-Junior; Angela Castela; Julie Carpentier; Vitalie Faoro; Malgorzata Klass; Miriam Cnop; Decio L Eizirik

Exercise as a non-pharmacological intervention to protect pancreatic beta cells in individuals with type 1 and type 2 diabetes Journal Article

In: Diabetologia, vol. 66, no. 3, pp. 450–460, 2023, ISSN: 1432-0428.

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Arturo Roca-Rivada; Sandra Marín-Cañas; Maikel L Colli; Chiara Vinci; Toshiaki Sawatani; Lorella Marselli; Miriam Cnop; Piero Marchetti; Decio L Eizirik

Inhibition of the type 1 diabetes candidate gene PTPN2 aggravates TNF-α-induced human beta cell dysfunction and death Journal Article

In: Diabetologia, 2023, ISSN: 1432-0428.

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Dario F De Jesus; Zijie Zhang; Natalie K Brown; Xiaolu Li; Matthew J Gaffrey; Sevim Kahraman; Jiangbo Wei; Jiang Hu; Giorgio Basile; Ling Xiao; Tariq M Rana; Clayton Mathews; Alvin C Powers; Mark A Atkinson; Decio L Eizirik; Sirano Dhe-Paganon; Audrey V Parent; Wei-Jun Qian; Chuan He; Rohit N Kulkarni

Redox Regulation of m A Methyltransferase METTL3 in Human β-cells Controls the Innate Immune Response in Type 1 Diabetes Working paper

2023.

Abstract | Links

Vyron Gorgogietas; Bahareh Rajaei; Chae Heeyoung; Bruno J. Santacreu; Sandra Marín-Cañas; Paraskevi Salpea; Toshiaki Sawatani; Anyishai Musuaya; María N. Arroyo; Cristina Moreno-Castro; Khadija Benabdallah; Celine Demarez; Sanna Toivonen; Cristina Cosentino; Nathalie Pachera; Maria Lytrivi; Ying Cai; Lode Carnel; Cris Brown; Fumihiko Urano; Piero Marchetti; Patrick Gilon; Decio L. Eizirik; Miriam Cnop; Mariana Igoillo-Esteve

GLP-1R agonists demonstrate potential to treat Wolfram syndrome in human preclinical models Journal Article

In: Diabetologia, 2023, ISSN: 0012-186X 1432-0428.

Links

Perrin Guyer; David Arribas-Layton; Anthony Manganaro; Cate Speake; Sandra Lord; Decio L Eizirik; Sally C Kent; Roberto Mallone; Eddie A James

Recognition of mRNA Splice Variant and Secretory Granule Epitopes by CD4+ T Cells in Type 1 Diabetes Journal Article

In: Diabetes, vol. 72, no. 1, pp. 85–96, 2023, ISSN: 1939-327X.

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Itziar González-Moro; Henar Rojas-Márquez; Maialen Sebastian-delaCruz; Jon Mentxaka-Salgado; Ane Olazagoitia-Garmendia; Luis Manuel Mendoza; Aina Lluch; Federica Fantuzzi; Carmen Lambert; Jessica Ares Blanco; Lorella Marselli; Piero Marchetti; Miriam Cnop; Elías Delgado; José Manuel Fernández-Real; Francisco José Ortega; Ainara Castellanos-Rubio; Izortze Santin

A long non-coding RNA that harbors a SNP associated with type 2 diabetes regulates the expression of gene in pancreatic beta cells Journal Article

In: Front Endocrinol (Lausanne), vol. 14, pp. 1101934, 2023, ISSN: 1664-2392.

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Kerstin Griess; Michael Rieck; Nadine Müller; Gergely Karsai; Sonja Hartwig; Angela Pelligra; Robert Hardt; Caroline Schlegel; Jennifer Kuboth; Celina Uhlemeyer; Sandra Trenkamp; Kay Jeruschke; Jürgen Weiss; Leon Peifer-Weiss; Weiwei Xu; Sandra Cames; Xiaoyan Yi; Miriam Cnop; Mathias Beller; Holger Stark; Arun Kumar Kondadi; Andreas S Reichert; Daniel Markgraf; Marianne Wammers; Dieter Häussinger; Oliver Kuss; Stefan Lehr; Decio Eizirik; Heiko Lickert; Eckhard Lammert; Michael Roden; Dominic Winter; Hadi Al-Hasani; Doris Höglinger; Thorsten Hornemann; Jens C Brüning; Bengt-Frederik Belgardt

Sphingolipid subtypes differentially control proinsulin processing and systemic glucose homeostasis Journal Article

In: Nat Cell Biol, vol. 25, no. 1, pp. 20–29, 2023, ISSN: 1476-4679.

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2022

Emanuele Bosi; Lorella Marselli; Mara Suleiman; Marta Tesi; Carmela De Luca; Silvia Del Guerra; Miriam Cnop; Decio L Eizirik; Piero Marchetti

A single-cell human islet interactome atlas identifies disrupted autocrine and paracrine communications in type 2 diabetes Journal Article

In: NAR Genom Bioinform, vol. 4, no. 4, pp. lqac084, 2022, ISSN: 2631-9268.

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Xiaoyan Yi; Bianca Marmontel de Souza; Toshiaki Sawatani; Florian Szymczak; Lorella Marselli; Piero Marchetti; Miriam Cnop; Decio L Eizirik

Mining the transcriptome of target tissues of autoimmune and degenerative pancreatic β-cell and brain diseases to discover therapies Journal Article

In: iScience, vol. 25, no. 11, pp. 105376, 2022, ISSN: 2589-0042.

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Vikash Chandra; Hazem Ibrahim; Clémentine Halliez; Rashmi B Prasad; Federica Vecchio; Om Prakash Dwivedi; Jouni Kvist; Diego Balboa; Jonna Saarimäki-Vire; Hossam Montaser; Tom Barsby; Väinö Lithovius; Isabella Artner; Swetha Gopalakrishnan; Leif Groop; Roberto Mallone; Decio L Eizirik; Timo Otonkoski

The type 1 diabetes gene TYK2 regulates β-cell development and its responses to interferon-α Journal Article

In: Nat Commun, vol. 13, no. 1, pp. 6363, 2022, ISSN: 2041-1723.

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Simranjeet Kaur; Caroline Frørup; Aashiq H Mirza; Tina Fløyel; Reza Yarani; Maikel L Colli; Jesper Johannesen; Joachim Størling; Decio L Eizirik; Flemming Pociot

Pro-Inflammatory Cytokines Promote the Transcription of Circular RNAs in Human Pancreatic β Cells Journal Article

In: Noncoding RNA, vol. 8, no. 5, 2022, ISSN: 2311-553X.

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Emanuele Bosi; Piero Marchetti; Guy Allen Rutter; Decio Laks Eizirik

Human alpha cell transcriptomic signatures of types 1 and 2 diabetes highlight disease-specific dysfunction pathways Journal Article

In: iScience, vol. 25, no. 10, pp. 105056, 2022, ISSN: 2589-0042.

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Florian Szymczak; Maria Inês Alvelos; Sandra Marín-Cañas; Ângela Castela; Stéphane Demine; Maikel Luis Colli; Anne Op de Beeck; Sofia Thomaidou; Lorella Marselli; Arnaud Zaldumbide; Piero Marchetti; Décio L Eizirik

Transcription and splicing regulation by NLRC5 shape the interferon response in human pancreatic β cells Journal Article

In: Sci Adv, vol. 8, no. 37, pp. eabn5732, 2022, ISSN: 2375-2548.

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Laura Giusti; Marta Tesi; Federica Ciregia; Lorella Marselli; Lorenzo Zallocco; Mara Suleiman; Carmela De Luca; Silvia Del Guerra; Mariachiara Zuccarini; Marco Trerotola; Decio L Eizirik; Miriam Cnop; Maria R Mazzoni; Piero Marchetti; Antonio Lucacchini; Maurizio Ronci

The Protective Action of Metformin against Pro-Inflammatory Cytokine-Induced Human Islet Cell Damage and the Mechanisms Involved Journal Article

In: Cells, vol. 11, no. 15, 2022, ISSN: 2073-4409.

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Corentin Scoubeau; Bruno Bonnechère; Miriam Cnop; Vitalie Faoro; Malgorzata Klass

Effectiveness of Whole-Body High-Intensity Interval Training on Health-Related Fitness: A Systematic Review and Meta-Analysis Journal Article

In: Int J Environ Res Public Health, vol. 19, no. 15, 2022, ISSN: 1660-4601.

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Mara Suleiman; Lorella Marselli; Miriam Cnop; Decio L Eizirik; Carmela De Luca; Francesca R Femia; Marta Tesi; Silvia Del Guerra; Piero Marchetti

The Role of Beta Cell Recovery in Type 2 Diabetes Remission Journal Article

In: Int J Mol Sci, vol. 23, no. 13, 2022, ISSN: 1422-0067.

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Julie Rodriguez; Audrey M Neyrinck; Maxime Van Kerckhoven; Marco A Gianfrancesco; Edith Renguet; Luc Bertrand; Patrice D Cani; Nicolas Lanthier; Miriam Cnop; Nicolas Paquot; Jean-Paul Thissen; Laure B Bindels; Nathalie M Delzenne

Physical activity enhances the improvement of body mass index and metabolism by inulin: a multicenter randomized placebo-controlled trial performed in obese individuals Journal Article

In: BMC Med, vol. 20, no. 1, pp. 110, 2022, ISSN: 1741-7015.

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Federica Fantuzzi; Sanna Toivonen; Andrea Alex Schiavo; Heeyoung Chae; Mohammad Tariq; Toshiaki Sawatani; Nathalie Pachera; Ying Cai; Chiara Vinci; Enrico Virgilio; Laurence Ladriere; Mara Suleiman; Piero Marchetti; Jean-Christophe Jonas; Patrick Gilon; Décio L Eizirik; Mariana Igoillo-Esteve; Miriam Cnop

In depth functional characterization of human induced pluripotent stem cell-derived beta cells and Journal Article

In: Front Cell Dev Biol, vol. 10, pp. 967765, 2022, ISSN: 2296-634X.

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Chieh-Hsin Yang; Danise Ann-Onda; Xuzhu Lin; Stacey Fynch; Shaktypreya Nadarajah; Evan G Pappas; Xin Liu; John W Scott; Jonathan S Oakhill; Sandra Galic; Yanchuan Shi; Alba Moreno-Asso; Cassandra Smith; Thomas Loudovaris; Itamar Levinger; Decio L Eizirik; D Ross Laybutt; Herbert Herzog; Helen E Thomas; Kim Loh

Neuropeptide Y1 receptor antagonism protects β-cells and improves glycemic control in type 2 diabetes Journal Article

In: Mol Metab, vol. 55, pp. 101413, 2022, ISSN: 2212-8778.

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2021

Quentin Leyrolle; Renata Cserjesi; Romane Demeure; Audrey M Neyrinck; Camille Amadieu; Julie Rodriguez; Olli Kärkkäinen; Kati Hanhineva; Nicolas Paquot; Miriam Cnop; Patrice D Cani; Jean-Paul Thissen; Laure B Bindels; Olivier Klein; Olivier Luminet; Nathalie M Delzenne

Microbiota and Metabolite Profiling as Markers of Mood Disorders: A Cross-Sectional Study in Obese Patients Journal Article

In: Nutrients, vol. 14, no. 1, 2021, ISSN: 2072-6643.

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Matt P Keasey; V Razskazovskiy; C Jia; E D Peterknecht; P C Bradshaw; T Hagg

PDIA3 inhibits mitochondrial respiratory function in brain endothelial cells and C. elegans through STAT3 signaling and decreases survival after OGD Journal Article

In: Cell Commun Signal, vol. 19, no. 1, pp. 119, 2021, ISSN: 1478-811X.

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Matt P Keasey; V Razskazovskiy; C Jia; E D Peterknecht; P C Bradshaw; T Hagg

PDIA3 inhibits mitochondrial respiratory function in brain endothelial cells and C. elegans through STAT3 signaling and decreases survival after OGD Journal Article

In: Cell Commun Signal, vol. 19, no. 1, pp. 119, 2021, ISSN: 1478-811X.

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Lorena Alonso; Anthony Piron; Ignasi Morán; Marta Guindo-Martínez; Sílvia Bonàs-Guarch; Goutham Atla; Irene Miguel-Escalada; Romina Royo; Montserrat Puiggròs; Xavier Garcia-Hurtado; Mara Suleiman; Lorella Marselli; Jonathan L S Esguerra; Jean-Valéry Turatsinze; Jason M Torres; Vibe Nylander; Ji Chen; Lena Eliasson; Matthieu Defrance; Ramon Amela; ; Hindrik Mulder; Anna L Gloyn; Leif Groop; Piero Marchetti; Decio L Eizirik; Jorge Ferrer; Josep M Mercader; Miriam Cnop; David Torrents

TIGER: The gene expression regulatory variation landscape of human pancreatic islets Journal Article

In: Cell Rep, vol. 37, no. 2, pp. 109807, 2021, ISSN: 2211-1247.

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Karolina Tyka; Anne Jörns; Alessia Dunst; Yadi Tang; Tenna Holgersen Bryde; Ilir Mehmeti; Anna Walentinsson; Lorella Marselli; Miriam Cnop; Björn Tyrberg; Michal T Marzec; Ewa Gurgul-Convey

MCPIP1 is a novel link between diabetogenic conditions and impaired insulin secretory capacity Journal Article

In: Biochim Biophys Acta Mol Basis Dis, vol. 1867, no. 10, pp. 166199, 2021, ISSN: 1879-260X.

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Audrey M Neyrinck; Julie Rodriguez; Zhengxiao Zhang; Benjamin Seethaler; Cándido Robles Sánchez; Martin Roumain; Sophie Hiel; Laure B Bindels; Patrice D Cani; Nicolas Paquot; Miriam Cnop; Julie-Anne Nazare; Martine Laville; Giulio G Muccioli; Stephan C Bischoff; Jens Walter; Jean-Paul Thissen; Nathalie M Delzenne

Prebiotic dietary fibre intervention improves fecal markers related to inflammation in obese patients: results from the Food4Gut randomized placebo-controlled trial Journal Article

In: Eur J Nutr, vol. 60, no. 6, pp. 3159–3170, 2021, ISSN: 1436-6215.

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Maria Inês Alvelos; Florian Szymczak; Ângela Castela; Sandra Marín-Cañas; Bianca Marmontel de Souza; Ioannis Gkantounas; Maikel Colli; Federica Fantuzzi; Cristina Cosentino; Mariana Igoillo-Esteve; Lorella Marselli; Piero Marchetti; Miriam Cnop; Décio L Eizirik

A functional genomic approach to identify reference genes for human pancreatic beta cell real-time quantitative RT-PCR analysis Journal Article

In: Islets, vol. 13, no. 3-4, pp. 51–65, 2021, ISSN: 1938-2022.

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Emanuele Bosi; Lorella Marselli; Carmela De Luca; Mara Suleiman; Marta Tesi; Mark Ibberson; Decio L Eizirik; Miriam Cnop; Piero Marchetti

Correction to ‘Integration of single-cell datasets reveals novel transcriptomic signatures of β-cells in human type 2 diabetes’

2021.

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Erling Tjora; Anny Gravdal; Trond Engjom; Miriam Cnop; Bente B Johansson; Georg G Dimcevski; Anders Molven; Karianne Fjeld

Protein misfolding in combination with other risk factors in CEL-HYB1-mediated chronic pancreatitis Journal Article

In: Eur J Gastroenterol Hepatol, vol. 33, no. 6, pp. 839–843, 2021, ISSN: 1473-5687.

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Quentin Leyrolle; Renata Cserjesi; Maria D G H Mulders; Giorgia Zamariola; Sophie Hiel; Marco A Gianfrancesco; Daphné Portheault; Camille Amadieu; Laure B Bindels; Sophie Leclercq; Julie Rodriguez; Audrey M Neyrinck; Patrice D Cani; Nicolas Lanthier; Pierre Trefois; Jérome Bindelle; Nicolas Paquot; Miriam Cnop; Jean-Paul Thissen; Olivier Klein; Olivier Luminet; Nathalie M Delzenne

Prebiotic effect on mood in obese patients is determined by the initial gut microbiota composition: A randomized, controlled trial Journal Article

In: Brain Behav Immun, vol. 94, pp. 289–298, 2021, ISSN: 1090-2139.

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Quentin Leyrolle; Renata Cserjesi; Maria D G H Mulders; Giorgia Zamariola; Sophie Hiel; Marco A Gianfrancesco; Julie Rodriguez; Daphnée Portheault; Camille Amadieu; Sophie Leclercq; Laure B Bindels; Audrey M Neyrinck; Patrice D Cani; Olli Karkkainen; Kati Hanhineva; Nicolas Lanthier; Pierre Trefois; Nicolas Paquot; Miriam Cnop; Jean-Paul Thissen; Olivier Klein; Olivier Luminet; Nathalie M Delzenne

Specific gut microbial, biological, and psychiatric profiling related to binge eating disorders: A cross-sectional study in obese patients Journal Article

In: Clin Nutr, vol. 40, no. 4, pp. 2035–2044, 2021, ISSN: 1532-1983.

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Maria Lytrivi; Valérie Senée; Paraskevi Salpea; Federica Fantuzzi; Anne Philippi; Baroj Abdulkarim; Toshiaki Sawatani; Sandra Marín-Cañas; Nathalie Pachera; Anne Degavre; Pratibha Singh; Céline Derbois; Doris Lechner; Laurence Ladrière; Mariana Igoillo-Esteve; Cristina Cosentino; Lorella Marselli; Jean-François Deleuze; Piero Marchetti; Décio L Eizirik; Marc Nicolino; Annabelle Chaussenot; Cécile Julier; Miriam Cnop

DNAJC3 deficiency induces β-cell mitochondrial apoptosis and causes syndromic young-onset diabetes Journal Article

In: Eur J Endocrinol, vol. 184, no. 3, pp. 455–468, 2021, ISSN: 1479-683X.

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Marta Tesi; Marco Bugliani; Gianmarco Ferri; Mara Suleiman; Carmela De Luca; Emanuele Bosi; Matilde Masini; Vincenzo De Tata; Conny Gysemans; Francesco Cardarelli; Miriam Cnop; Decio L Eizirik; Piero Marchetti; Lorella Marselli

Pro-Inflammatory Cytokines Induce Insulin and Glucagon Double Positive Human Islet Cells That Are Resistant to Apoptosis Journal Article

In: Biomolecules, vol. 11, no. 2, 2021, ISSN: 2218-273X.

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Jean-Charles Preiser; Miriam Cnop

Perioperative Management of Glucose-lowering Drugs: Reply Journal Article

In: Anesthesiology, vol. 134, no. 2, pp. 350–351, 2021, ISSN: 1528-1175.

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Neha Shrestha; Elisa De Franco; Peter Arvan; Miriam Cnop

Pathological β-Cell Endoplasmic Reticulum Stress in Type 2 Diabetes: Current Evidence Journal Article

In: Front Endocrinol (Lausanne), vol. 12, pp. 650158, 2021, ISSN: 1664-2392.

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90 entries « 1 of 2 »